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My heart so goes out to you. I know the waiting on the test results is so hard - and then you are faced with hard decisions to make. I hope there will be a good treatment plan for Kaizer that will help him be well and feel well. As the oncologist told me last week, chemo therapies have come a long way even just in the past decade. Hopefully both of our pups will benefit from that.
 

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Discussion Starter · #162 ·
My heart so goes out to you. I know the waiting on the test results is so hard - and then you are faced with hard decisions to make. I hope there will be a good treatment plan for Kaizer that will help him be well and feel well. As the oncologist told me last week, chemo therapies have come a long way even just in the past decade. Hopefully both of our pups will benefit from that.
I’ve heard dogs react to the chemo better than humans do, so I’m hopeful.

If Kaizer does have the indolent lymphoma, usually its not treated until the disease becomes “active” whether that means there’s bloodwork changes or the lymph nodes get big. Kaizer’s oncologist was talking about starting him on an oral chemo (chlorambucil) and prednisone if has has the indolent cancer - I’m nervous this means she thinks his cancer is already active.

I’m sorry you and Shala are going through this too. Both of our dogs are far too young for all this!
 
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I am so sorry to hear about Kaizer. I hope you get more answers and that it is a slow growing type. I'm glad he's feeling a bit better.
 

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I’ve heard dogs react to the chemo better than humans do, so I’m hopeful.
The oncologist did say this to me, too, so good reason to be hopeful. Ten years ago, chemo made my last dog very nauseous and lethargic. It was tough to get her to eat anything, and so she just got so weak. I am definitely heartened to hear that there have been positive developments and that this kind of reaction is not expected this time. Fingers crossed it is the same for Kaizer, too.
 
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Discussion Starter · #165 ·
Kaizer’s flow cytometry results came back inconclusive - because of course. So now we don’t really even know if we’re dealing with cancer. Cytology said yes, lymphoma. Flow said maybe not. Our last step is the PARR test which will only tell us if he’s “negative” for cancer or “positive” for cancer and if positive, if it’s B-call or T-cell lymphoma, but won’t tell us if its the indolent version of the cancer. The good news is that if it comes back negative, then he most likely doesn’t have cancer. If it comes back positive, then he definitely does have cancer.

Downside is that the PARR test takes forever and it might be another 2 weeks before getting results back. So clearly I’m feeling great and I’m so not anxious at all for this LOL.
 
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You need to change his name to Conundrum. I'm hoping this is actually good news.
 
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Kaizer’s flow cytometry results came back inconclusive - because of course. ...
Downside is that the PARR test takes forever and it might be another 2 weeks before getting results back. So clearly I’m feeling great and I’m so not anxious at all for this LOL.
More waiting. I know, it is so so hard. But if it will give you a definitive answer, it will be worth the wait. And fingers crossed, it will be negative. That would be such a relief. (Though I know, more mystery).Try not to think about it for the two weeks. That helped me as I waited for the advanced tumour testing. Hoping he will continue to feel well and happy in the meantime!
 
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Discussion Starter · #169 ·
You need to change his name to Conundrum. I'm hoping this is actually good news.
ha! yes he certainly does seem to be throwing everyone for a loop.
 

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Discussion Starter · #170 ·

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Discussion Starter · #171 ·
More waiting. I know, it is so so hard. But if it will give you a definitive answer, it will be worth the wait. And fingers crossed, it will be negative. That would be such a relief. (Though I know, more mystery).Try not to think about it for the two weeks. That helped me as I waited for the advanced tumour testing. Hoping he will continue to feel well and happy in the meantime!
definitely worth the wait!! I’m just trying to enjoy the time I have with him now and not panic about what could be (so much easier said than done). Also trying to look at overall behavior patterns vs focusing on specific little changes (because if there’s anything ive learned about vet med through him, its super hard to catch things really early).
 
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Discussion Starter · #172 ·
I have spent so many months watching Kaizer very intently for any changes in his behavior that now that he seems OK for the most part, I kinda don’t know what to do (it’s a good thing, but such a change). The things I AM noticing, I don’t know if they mean anything or if it’s just a “Kaizer special”.

He’s losing fur - bald spots behind his ears/elbows, his chest fur has significantly decreased, his paw/toe fur hasnt grown in at all since his groom a month ago (!), the fur on the back of his front legs has significantly decreased, there’s no furnishings on his hocks, and even his butt fluff is coming out in tufts. His stomach fur has barely started to grow back since it was shaved in July! He looks like an alien

He’s been drinking a lot of water, and he lost weight again despite me not trying to get him to lose weight. He’s down to 75# from 80# in 1-2 weeks (I don’t remember if I weighed him last week or the week before).

885140

(he was bloated in this pic).
 

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Discussion Starter · #173 ·
So he may not have lymphoma! PARR test also came back negative. Oncology isn’t in until Monday, so I talked to his IMS just to bounce ideas off of her.

She says it’s possible that he’s got some kind of autoimmune disorder, but she doesn’t completely rule out cancer either. She said If I’m still concerned, the next step could be to surgically remove an enlarged lymph node and send it in for histopathology that way they can get multiple samples.

I’m unsure what I want to do. He’s still doing well, all things considered. The dr who did his cytology specializes in lymphomas, so I’m just at a loss. I’ll wait for oncology to get in touch with me, but I just don’t know what to do. I wish there was a clear answer.

My worst fear is that it takes too long to get a solid diagnosis and by thay point it’ll be too late. The flip side is I feel like if he definitely had cancer, I’d have a definite diagnosis.
 

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I'm sorry you don't have a definite diagnosis yet.

Try to remain as optimistic as you possibly can, not only for him but for yourself as well.
 

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So he may not have lymphoma! PARR test also came back negative. Oncology isn’t in until Monday, so I talked to his IMS just to bounce ideas off of her.

She says it’s possible that he’s got some kind of autoimmune disorder, but she doesn’t completely rule out cancer either. She said If I’m still concerned, the next step could be to surgically remove an enlarged lymph node and send it in for histopathology that way they can get multiple samples.

I’m unsure what I want to do. He’s still doing well, all things considered. The dr who did his cytology specializes in lymphomas, so I’m just at a loss. I’ll wait for oncology to get in touch with me, but I just don’t know what to do. I wish there was a clear answer.

My worst fear is that it takes too long to get a solid diagnosis and by thay point it’ll be too late. The flip side is I feel like if he definitely had cancer, I’d have a definite diagnosis.
So glad all things are pointing to not cancer. Probably best to follow the advice of the vet, but removing a lymph node when things are suggesting not cancer, seems a bit extreme. Is there anything you can do to explore the autoimmune disorder route? Thinking of all of this symptoms, it seems like it could be a fit. Feel so bad that he's losing weight and hair. At least he's in good spirits!
 

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Discussion Starter · #176 ·
So glad all things are pointing to not cancer. Probably best to follow the advice of the vet, but removing a lymph node when things are suggesting not cancer, seems a bit extreme. Is there anything you can do to explore the autoimmune disorder route? Thinking of all of this symptoms, it seems like it could be a fit. Feel so bad that he's losing weight and hair. At least he's in good spirits!
No idea!! We’ll see what onco says, but I suspect they won’t be concerned either.
Is it terrible that I probably won’t do anything any further as long as he’s feeling okay? He’s not 100%, but I don’t think he’ll ever be 100% again. I dont want to miss anything but I really feel like if he had cancer, we’d know for sure?
 

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Discussion Starter · #177 ·
I am very anxious about all this. I really hate being told he has cancer and then being told he doesn’t. I also hate not knowing what’s gonna happen in the future, like if I knew he’d live for years, I wouldn’t be stressing about this. But he could decline and pass at any point and I’ll always have guilt that I just didn’t do more for him.

But here he was yesterday with Eden.. a really sick dog wouldn’t be running and playing, right?
885221
 

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No doubt this has had wear and tear on your emotions. I'm not an expert, but, I agree that if he had cancer you'd think the tests would be definitively positive. I do still think there is something going though. The weight loss and hair loss, the recent stroke - things things are not normal. But, I'm also not sure what else you could do for him at this point. It is so hard because it does seem like there is something going on, but, no one can pinpoint what it is... which, makes it impossible to treat, and impossible to know roughly how long you will have with him. One things for sure, no one will doubt that you did everything you could for him when his time does come. Hopefully a long time from now.
 

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No doubt this has had wear and tear on your emotions. I'm not an expert, but, I agree that if he had cancer you'd think the tests would be definitively positive. I do still think there is something going though. The weight loss and hair loss, the recent stroke - things things are not normal. But, I'm also not sure what else you could do for him at this point. It is so hard because it does seem like there is something going on, but, no one can pinpoint what it is... which, makes it impossible to treat, and impossible to know roughly how long you will have with him.
I agree with this. There does seem to be something going on, and from what little I know about autoimmune disorders, they can be REALLY hard to diagnose and sometimes they are never definitively given a named diagnosis. I don't think it is awful to do nothing if he is feeling well. But he seems to have good spurts and bad spurts, which has been telling you that something is wrong (and which you have been AMAZING in responding to). I can feel your frustration - it would be maddening to me to know there is something wrong but not know what it is. Are there vet specialists in autoimmune disorders? That might be a route to explore? Hang in there...
 
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