How much is he on?? And what is it for?? Cody was on 1 mg per lb of body weight for an auto immune anemia. He had increased thirst and urination and a voracious appetite. Panted some but not excessively. Did not have trouble getting up.... in fact, pred usually masks discomfort and makes them feel better. If I were you, I'd get a call in to the vet just to make sure this is to be expected.