My sweetheart Molson who is quickly approaching 15 has hip dysplasia, spinal nerve damage and you can throw in arthritis. At this stage of the game, he is on pain management plus...the tramadol 150 mg 3x's a day, certainly keeps him comfortable, he never whimpers like he had when he wasn't on it. he is also on metacam 35kg and glucosamin/chondrotin, all this helps. We know all about side effects but so far so good. And he uses the Hip Hammock (Animal Assistance Products) to help him walk and keep active, which and I hate sounding like an infomercial but is a walking support I developed for Molson to help him thrive. And most important I believe for dogs with joint issues to keep him mobile and moving to help keep him limber or as limber as possible! He is happy, hungry and bright eyed! Right now sitting on our front porch talking to the neighbours.