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This is an odd question. I am assuming you actually mean a collar + leash versus a harness + leash. I would definitely go with the harness + leash option. If your puppy gets spooked by anything along the way, this will be far more secure. It would be a nightmare if she/he slipped the collar on you, and endangered themselves.
I think the option to have them go on pads depends on if you will be stopping in areas highly frequented by other dogs or not and/or if there is many cases of Parvo in your area. Your vet should be able to tell you this. Either way it shouldn't deter their potty training to have them go on pads along the way. At the very least, you should wipe their paws with hypoallergenic sanitation wipes for dogs before getting back on the road. Try to not let them eat any of the grass etc. while going potty too.
I think the option to have them go on pads depends on if you will be stopping in areas highly frequented by other dogs or not and/or if there is many cases of Parvo in your area. Your vet should be able to tell you this. Either way it shouldn't deter their potty training to have them go on pads along the way. At the very least, you should wipe their paws with hypoallergenic sanitation wipes for dogs before getting back on the road. Try to not let them eat any of the grass etc. while going potty too.