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post #21 of 32 (permalink) Old 11-11-2019, 09:16 AM Thread Starter
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https://photos.app.goo.gl/8F35eVSzTYdJG8eUA


If this works, this is a short video of what he was doing before the vet put him on pheno. Also, if it works, thanks OscarsDad!
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post #22 of 32 (permalink) Old 11-11-2019, 10:57 AM
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Originally Posted by sopranosgal View Post
https://photos.app.goo.gl/8F35eVSzTYdJG8eUA


If this works, this is a short video of what he was doing before the vet put him on pheno. Also, if it works, thanks OscarsDad!
It works. I'm sorry you are going through this with your sweet baby. If you have access to one and are able, I'd take him to a neurologist.
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post #23 of 32 (permalink) Old 11-11-2019, 11:32 AM
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There are other seizure medications that can be used if he is having an adverse reaction to the phenobarbital. I really think you should take him in to your vet and have them look at him. Animals and humans all react to seizure medications differently. What works for one doesn't always work for all. Seizure medicines save lives and improve the quality of them everyday, but you have to find the right one.

Well wishes sent your way!
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post #24 of 32 (permalink) Old 11-11-2019, 07:35 PM
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Oh, he looks like such a sweetheart.

DblTrblGolden2 is absolutely right. There are other newer anti-seizure meds that are less likely to cause ataxia (and lethargy). If I were you, I would take him to a veterinary neurologist.

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post #25 of 32 (permalink) Old 11-22-2019, 02:03 PM Thread Starter
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So Jake has been on the Pheno for 2 weeks today. His ataxia had gotten better. He has a hard time getting up, but once he is up, he is good. The actual seizures stopped but I feel like he had the pre seizure symptoms without us actually seeing the seizure. Two hours ago, he had a real focal seizure for the first time since the meds. It lasts only a few seconds just like it did before the mded. We have a neuro appt Monday at 9. I was starting to feel optimistic but not anymore.
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post #26 of 32 (permalink) Old 11-30-2019, 11:08 AM Thread Starter
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Took Jake to the neurologist this past Monday. He said he wasn't convinced it was seizures. It could be something like what people experience as tics. He said we had 3 choices: First choice was to do an MRI and we can find out for sure what is going on. This test cost $5000 and unfortunetly we are not in the financial positiion to do that.

Second choice was to do a complete blood work up for $700. This may or may not tell us what is wrong. Third choice was to mix and match medications until he found some relief.
We chose to do the bloodwork. The only thing this showed us was that his organs etc are functioning normally and his levels are all ok. They put him on gabapentin. This medicine is used for pain from arthritis, cancer etc and also for seizures. In addition, he is still on the phenobarbital.
We have been giving him the gabapentin since Wednesday night. We are noticing his "twitches", Seizures, Tics....whatever they are seem to be worsening. He is also barking a lot. We are at a loss. We have a call into the Neuro to see what we should do.
Has anyone else been prescribed gabapentin for their dogs seizures etc?
Feeling a little desperate.
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post #27 of 32 (permalink) Old 11-30-2019, 03:45 PM
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I hope the Neuro can help you solve this issue for Jake.
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post #28 of 32 (permalink) Old 11-30-2019, 05:45 PM
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I am sorry for what you and Jake are going through. It is frustrating to go through vets, specialists and not getting a proper diagnosis. Unfortunately, seizures, especially with aging dog may have many different origins.

One possibility is Jakeís seizures are related to his decreasing renal function. It is not uncommon myoclonic seizures (I think this is what I see in the video, uncontrolled muscle movement and twitching) accompany the progression of kidney disease.
You say Jake had his full blood work and it was OK. Do you do urine tests to assess the progression of his renal disease? Does he have proteinuria, what is his urine concentration? The blood parameters can be perfectly normal until about 85% of kidneys function are compromised. My dog had perfect blood readings the same week he passed away from kidney failure, but he had severe proteinuria and his urine concentration was 0 for a few months before he died. For us the first sign of the problem was also his hind legs giving away. There are many reasons for this, but one of them is the renal failure.
Gabapentin can worsen myoclonic seizures. See the link to the epilepsy journal. With renal disease and seizures, the recommend medications are from benzodiazepines family.
Treating seizures in renal and hepatic failure

Keeping Jake on enalapril is a good thing. Do you measure his blood pressure; maybe he needs a higher dose of enalapril. In addition, you mention Jake is on home cooked diet (my dogs as well). You want to feed him high quality, low protein diet (egg whites, fish etc) avoiding too much phosphorus.
I also recommend CBD oil. I currently have a dog with some sort of neurological movement issue. It might be seizures, though if they are they are very different from the typical ones. I think he has paroxysmal dyskinesia so the AED drugs donít work anyway. My guy was on gabapentin for a bit but it didnít work.

Good luck to you and Jake! Please keep us posted. I hope for no more seizures.

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post #29 of 32 (permalink) Old 12-01-2019, 11:57 AM Thread Starter
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You gave me some interesting information. When I looked up myoclonic seizures, it sounds like him. I have a call in to the neurologist to talk to him about it but I doubt I will hear until tomorrow. You did scare me though when you told me your pup died the same week his bloodwork was o.k. I am very sorry. His urine hasn't been tested since May. That also makes me wonder why the neurologist didn't include this in his testing.

Although knowledge is power, I don't think looking up too many things on the internet is the right choice for me. I get overwhelmed and panicked. I'm trying to just write my questions down, keep a journal and wait for the doctor.

By the way, can myoclonic seizures be treated? Do you know if they are in pain from them?
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post #30 of 32 (permalink) Old 12-02-2019, 09:49 AM Thread Starter
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Neuro said to stop the gabapentin. Added another 15 mg to Pheno. I guess the ataxia may increase again.
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