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Old 06-06-2011, 11:05 PM
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Trifexis, Sentinel, Heartguard?

Is anybody using Trifexis for their golden puppy? I started with Sentinel but switched vet and the new vet suggested using Trifexis. Read some comments on petmed.com that dogs who took that had some side effects of vomiting. Anybody has experience with Trifexis? I also think that trifexis (~$21 per pill) is more expensive than sentinel per pill since i'm getting 1 at a time from the vet till my dog hits the 50Ibs mark.

Or are there other recommendations for heartworm pills and flea+tick pills?
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Old 06-06-2011, 11:07 PM
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Most people in my area use Interceptor for their HW medication (as do I). We also carry Heartguard which is the second most popular. We have Sentinel, but I have never sold a box... ever.

I don't know of any flea and tick pills, but for topical I use Frontline Plus and we also carry Vectra 3D
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Old 06-06-2011, 11:19 PM
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Interesting about the vomiting... o_O

I've never had any problems with Sentinel. But honestly - if you live in an area with a lot of ticks and fleas, you probably need something more than Sentinel.

Our collie is on Advantage Multi (covers worms including heartworm and kills fleas). The only thing I've noticed is that it probably stings or is uncomfortable for him after application. It's not as drastic as our cat when he gets the Revolution treatment (he runs and hides for a few hours, so is probably very uncomfortable for him). <- It's why I would prefer to stay away from topicals with my golden.
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Old 06-06-2011, 11:25 PM
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All trifexis is...is the combination of interceptor and comfortis. If u give comfortis on an empty stomach, they can vomit it up. So that is why there is a warning for trifexis. Being from the south where fleas are crazy....sentinel will not work! Atleast not for me. So trifexis covers everything Interceptor covers plus fleas. My brother just started using it and is happy with it. I still use heartgard.
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Old 06-06-2011, 11:27 PM
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We use Heartguard Plus currently. We have used Interceptor in the past. Basically, we switched vets and this vet carries and recommends Heartguard Plus. We haven't had any problems with either of them. Fleas aren't a concern for us, so we don't have a need to include that component of the meds.
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Old 06-06-2011, 11:38 PM
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I'm going to switch to Trifexis when the 6 month supplies of Comfortis and Iverhart I've bought run out. The same warning about vomiting is on the Comfortis boxes, and neither of my dogs have ever had any issues with it. I usually give the pill to them before their dinner.

Yes, it is more expensive per pill than Sentinel, but it's a better product, IMO, if fleas are bad in your area or your dog is flea bite allergic. It will actually kill fleas, Sentinel will just make fleas infertile when they bite, so they can't lay eggs that will make more fleas.
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Old 06-07-2011, 02:15 PM
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I am using Trifexis on my girls plus a Scalibor tick collar. Unfortunately if you need tick protection there is no pill for them, so you get to decide if you want to use a topical that gets ticks or use a collar like Scalibor or Preventic. If you are going to be using a topical flea/tick med, I'd go with Heartgard Plus or Interceptor. If ticks aren't a concern I much prefer Trifexis to Sentinel since Sentinel doesn't actually kill fleas.

As to the vomiting-yes, Trifexis (and Comfortis) occasionally causes vomiting. It is less likely if you give the pill with a meal. Supposedly, it does not appear to be a repeatable issue meaning that just because your dog vomited last month does not mean it will vomit the pill again. If your dog does vomit the pill, call your vet and they will replace the pill so you can redose the dog (the company will replace the pill to the vet).
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Old 06-07-2011, 02:24 PM
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We've got Izzy on Trifexis based on the vet's suggestion. The only trouble I have is getting Miss Izzy to eat it. If I cover it in peanut butter, she'll eventually eat it but it takes some work.
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Old 11-20-2012, 11:00 AM
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No, No, No to Trifexis!!!

Why on earth would you give your dog a flea pesticide that you have to take orally??? Putting it in his bloodstream? Plus, the fleas have to bite the dog before they can die so if your dog is allergic to flea bites that would be a problem. I still swear by Frontline. I give it every single month and have been since My Ally came home in 2002 and I have never seen a flea...and I live in Georgia, a flea haven. Trifexis also does nothing for Ticks...which is a big deal since even one can cause big health issues.
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Old 11-20-2012, 11:13 AM
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I have always used Heartguard for heartworm and in the last few years have switched to Comfortis for fleas as the other products were becoming less than effective.
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