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post #1091 of 2781 (permalink) Old 11-29-2012, 10:23 PM
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Hannah is taking Carboplatin, a platinum based chemotherapy, that is also used with osteosarcoma. The primary side effects are nausea, diarrhea, vomiting and low white blood count. They actually didn't even mention hair loss to me. When I told them what happened, they said it was extremely rare and hair loss usually was associated with dogs with hair (poodles, etc), not fur, and that sometimes cats lost whiskers.

Approximately a week after Hannah's first dose of chemo, I noticed a few clumps of matted fur on the floor. I decided to give her a good brushing and that's when I noticed that her entire undercoat had lifted away from her body. It was almost like a piece of felt (matted and solid) that was floating just away from her body, but held to her body by her outer coat. I had to use an undercoat rake and pin brush to remove it all.

On really cold days, I've put Hannah's thundershirt on her for warmth. Truthfully though, I'm not sure she's really that cold. We aren't outside for long periods, so it might not be a problem for her. We've had temperature swings from 29F to 69F over the last week. Oh, also, when we sit outside during the day, I do cover her with a towel if it's chilly.

Aside from the IV shaves, he's missing a good bit of hair from the peak of her skull to her shoulder blades and then down her sides a bit, her rear end and part of the base of her tail are shaved, her underside and bit of her side from the abdominal ultrasound, a square near her heart from the ekg/echo AND she's missing an area on her lower back the size of two hand prints (from the epidural). The later is the one that's had virtually no hair regrowth.
Ooooh. That must have been scary. My stomach actually flipped when I read the bit about her undercoat lifting away. And with no warning to you! Definitely hard on you - and Hannah. Poor girl. It does sound like it's warmer where you are, but still, that's a lot of fur she is missing. I wonder if the chemo is keeping the shaved areas from growing back at a normal rate? I can't remember how long it took Tesia to grow back her fur after her abdominal ultrasound a few years ago. I was less worried because it happened in April or May and was getting warmer. Oh, I hope Hannah's fur grows back soon.

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post #1092 of 2781 (permalink) Old 11-29-2012, 10:28 PM Thread Starter
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Ooooh. That must have been scary. My stomach actually flipped when I read the bit about her undercoat lifting away. And with no warning to you! Definitely hard on you - and Hannah. Poor girl. It does sound like it's warmer where you are, but still, that's a lot of fur she is missing. I wonder if the chemo is keeping the shaved areas from growing back at a normal rate? I can't remember how long it took Tesia to grow back her fur after her abdominal ultrasound a few years ago. I was less worried because it happened in April or May and was getting warmer. Oh, I hope Hannah's fur grows back soon.
It was very weird when it happened. I'd read about rare, but possible hair loss with other chemos, but not carboplatin.

Chemo does slow hair regrowth - so I'm trying really hard to be patient, since Hannah's not bothered by it. The oncology surgeon said she looks like a patchwork quilt
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post #1093 of 2781 (permalink) Old 11-29-2012, 10:50 PM
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I am so glad to hear the cardiologist gave you good news. I know a little bit about heart murmurs and the fact that he said he doesn't need to see Hannah for a while means (I think) that she's stable. I don't know why the grade is IV/VI either. Maybe its in the 4 thru 6 range; varies in her recent tests.

And as long as Hannah is warm enough, her hair loss isn't a problem for her. Dogs are great and such a reality check for me. Sometimes I think a lighter coat would be a good thing for finding skin problems early. I just had Chance to the vet yesterday to recheck some lumps, bumps and skin problems we have been watching. I had trouble finding one I wanted to have the vet examine. But of course I find it easily when I am at home with him.

I am thinking of you and Hannah and glad you are having good times together.

..... have a Golden day
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post #1094 of 2781 (permalink) Old 11-29-2012, 10:59 PM
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I am happy for good news and glad that Hannah is eating and feeling better. Hope weekend is calm and good one for you two.


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post #1095 of 2781 (permalink) Old 11-29-2012, 11:43 PM
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Happy Hannah Our Katie has had a heart murmur the 8+ years she's been with us. Doesn't affect her. Same thing with the hair loss. His coat has never grown back completely, but it's getting better and better month to month. Thank god they aren't vain or we'd also have them going to the Hair Club. LOL


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post #1096 of 2781 (permalink) Old 11-29-2012, 11:46 PM
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Glad she got her 2nd round of chemo. I hope the UTI goes away quickly. How does Hannah feel after chemo?

I hope your car issues go away very quickly!

Lauren, Luna and Rory!

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post #1097 of 2781 (permalink) Old 11-30-2012, 04:46 AM Thread Starter
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I am so glad to hear the cardiologist gave you good news. I know a little bit about heart murmurs and the fact that he said he doesn't need to see Hannah for a while means (I think) that she's stable. I don't know why the grade is IV/VI either. Maybe its in the 4 thru 6 range; varies in her recent tests.

And as long as Hannah is warm enough, her hair loss isn't a problem for her. Dogs are great and such a reality check for me. Sometimes I think a lighter coat would be a good thing for finding skin problems early. I just had Chance to the vet yesterday to recheck some lumps, bumps and skin problems we have been watching. I had trouble finding one I wanted to have the vet examine. But of course I find it easily when I am at home with him.

I am thinking of you and Hannah and glad you are having good times together.
I agree with you about her being stable. Personally I was relieved for the clearance - with everything else going on, it was nice to get a "pass" even if she does have heart issues. It actually wasn't the murmur that prompted the ekg/echo. She has an aortic arch that they were concerned about.

After my post, I found this site that explains heart murmurs: Heart Murmurs - - According to table 4, a IV/VI means "Loud intensity without a precordial thrill"

I hope Chance didn't have any problematic lumps/bumps at the vet. Sometimes I snip the hair near a lump in order to locate it again. I've also marked her up with a permanent marker too

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I am happy for good news and glad that Hannah is eating and feeling better. Hope weekend is calm and good one for you two.
Thanks - I hope things are calm(er) with little Charlie at your house It's so funny reading about his adventures. I distinctly remember at our first puppy obedience class, the teacher said that we should know that all puppies are meant to try our patience. She added that years down the road we would forget about those trying "puppy days and nights" and we'd hear others talk about their new puppy and we'd think "My sweetie never did that!" - she said that being able to look back with a smile and good humor is what allows us to have another pup come into our lives and our hearts down the road.

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Happy Hannah Our Katie has had a heart murmur the 8+ years she's been with us. Doesn't affect her. Same thing with the hair loss. His coat has never grown back completely, but it's getting better and better month to month. Thank god they aren't vain or we'd also have them going to the Hair Club. LOL
I keep reminding myself that she's not bothered by the missing hair. A former neighbor had a large Maine Coon cat that was always into trouble (he'd regularly come home covered in mud, grease, with stickers matted in his fur, you name it), so she started had him shaved. Poor boy hid for about a month until his hair started to regrow!

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Glad she got her 2nd round of chemo. I hope the UTI goes away quickly. How does Hannah feel after chemo?

I hope your car issues go away very quickly!
Thank you - thankfully, the car issues are resolved and it wasn't "quite" as bad as they thought, so I am thrilled!

The first round of her chemo, she was fine for the first 24 hours then was clearly nauseated for about 24 hours. She didn't vomit, but she looked like she felt awful and wasn't interested in eating or doing anything else (no tail wags, dull eyes, etc).

This time she was fine for about 12 hours and then had similar symptoms as before for about 2 days, but more intense. In addition to the previous stuff, she slept heavily or laid with her eyes barely open, wouldn't raise her head, refused to acknowledge visitors and would only step out the door to go to the bathroom and then immediately want to come back inside.

Once she went past the 24 hour window and was still feeling bad, I started getting worried and more worried.Around the 48 hour mark, a neighbor (who'd stopped by to check on her for me while I was at work) phoned to say that that Hannah was up, rolling around on the carpet and had been on a walk - I was so happy. I hope since this is the maximum dose that this will be the maximum side effect, but I'm just taking things a day at a time.
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post #1098 of 2781 (permalink) Old 11-30-2012, 08:54 AM
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I am glad that Hannah is doing so well, and hope that the UTI will pass quickly.
I think dogs are so much more resilient than us humans. And..... dogs don't complain....

Hugs to sweet Hannah! I hope you all have a great uneventful weekend ahead!
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post #1099 of 2781 (permalink) Old 11-30-2012, 09:44 AM
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Poor Hannah, those side effects sound awful. She must not have eaten much. It is scary when they don't bounce back as fast as they did after the first treatment. That is great news she is starting to feel better. I would get all nervous seeing my neighbor calling, but I’m glad it was a good call! Hopefully you two will have a nice relaxing weekend. When is her chemo schedule? How many more does she have?

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post #1100 of 2781 (permalink) Old 11-30-2012, 09:53 AM
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Hello all! This week has been brought to you by the letter C - Chemo, cardiology, clavamox and car issues.

Hannah got her second round of chemo, despite the suspected UTI. They gave her the full dose this time and the first two days were rough. She's finally feeling better though and has decided to eat more.

Her cardiology appt went well and they've basically released her for the next 12 months. One thing I find strange is they give her heart murmur a grade of IV/VI (I'm assuming it's 4/6? - so why isn't it just grade 5?? - I keep meaning to ask).

The UTI is back, so she's back on Clavamox. I'm thankful it's treatable with a number of antibiotics though. The Dr said she may need to be on a maintenance dose of Clavamox while on chemo, but wanted to talk to the other Drs about it.

Car issues - ugh. Thankfully, we're up and running again

We're so ready for the weekend - hope you all are too!
Thanks for the report by the letter C. I hope next week is brought to us by the letters G and H --she's doing GREAT and is HEALTHY!!
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